How to Optimize Patient Recruitment

Clinical trial advertising can be a sticky challenge to navigate. Randomized controlled trials, or RCTs, can be considerably hampered by lack of proper recruitment. This is, in many cases- so many that they’ve been assigned the tongue in cheek terms Muench’s Third Law and Lasagna’s lawresults from the trial-staff’s overestimation of the amount of people who meet their criteria.
How does this relate to Clinical trial advertising?
If patients are recruited inefficiently, serious consequences occur. Either the trial will need to be extended at further cost, or the results of the trial will be significantly delayed, meaning potentially valuable treatments and information don’t reach the public. Sometimes, the sample size will also have an effect on whether there’s even any use in running the trial for data integrity. Things that can hamper patient recruitment include patient’s preferences for certain therapy types, a lack of understanding of the complex nature of the trial, fear of a negative outcome and receiving inferior treatment. Some physicians also state trial complexity as a reason for not enrolling patients, and difficulty getting informed consent. When trying to design patient recruitment advertising, this must be addressed.
You must have a strategy
This all means that it’s vital that every clinical trial advertisement has a proper strategy that’s been tailored to the needs of the study. Firstly, you should know whether you need all patients to start the trial simultaneously, in batches, in drops and drops, or whether you’re just going to opt to recruit until a certain arbitrary date. There is a ton of strategies open for recruiting patients once this has been decided.  Media adds both traditional- TV, radio, Newspaper etc- and online can be used to great effect, and online source are usually t the least cost of all available methods. Physician referrals can produce very suitable candidates, while press releases, fliers, posters and cold calls can produce negligible results unless you have specific reason to believe they will be effective for you.Recruitment is, unfortunately, an unpredictable field, and statistics suggest less than 50% of eligible patients are possible to recruit. This is fine for ‘simple ‘data sets where a large pool of candidates exist, but not so much for more specialized areas
What should I consider?
Clinical trial advertising needs to consider that patients are put off by what they don’t understand.Paperwork and excessive administration appeals to no one. While sometimes such complexity can’t be avoided, it’s always best practice to attempt to streamline this as much as possible. Your trial must also be ethical and pass international ethical standards. You must be able to properly produce your relevance to interested stakeholders and patients alike. Emphasis the benefits to them, the society and medicine. You can use the practitioners who you are intending to include in the study asa preliminary screening process to get an idea of sample size, feasibility and to identify problems early in the planning process. Optimizing clinical trial advertisement is not for the faint hearted, but vital if you want to make your study feasible.